Corosolic acid ( Glucosol )

Catalog No. M18562 CAS No. 4547-24-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Corosolic acid
Note

Research use only, not for human use.
Brief Description

Corosolic acid contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1.
Description

Corosolic acid is a pentacyclic triterpene acid found in Lagerstroemia speciosa. It is similar in structure to ursolic acid, differing only in the fact that it has a 2-alpha-hydroxy attachment. Corosolic acid has numerous biological properties, including antidiabetic, anti-inflammatory, antiproliferative, and protein kinase C inhibition activity. However, there is a lack of clinical evidence to support these uses.
Synonyms

Glucosol
Pathway

JAK/STAT Signaling
Target

STAT
Recptor

FAK
Research Area

Cancer
Indication

——

CAS Number

4547-24-4
Formula Weight

472.7
Molecular Formula

C30H48O4
Purity

98%
Solubility

DMSO : ≥ 50 mg/mL 105.78 mM; H2O : < 0.1 mg/mL
SMILES

C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]3[C@@]4(C[C@H]([C@@H](C3(C)C)O)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O
Chemical Name

(2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid

1. Yoo KH, et al. Phytother Res. 2015 May;29(5):714-23.

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